Maternal antibody against pertussis.

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Maternal Immunization Earlier in Pregnancy Maximizes Antibody Transfer and Expected Infant Seropositivity Against Pertussis

BACKGROUND Maternal immunization against pertussis is currently recommended after the 26th gestational week (GW). Data on the optimal timing of maternal immunization are inconsistent. METHODS We conducted a prospective observational noninferiority study comparing the influence of second-trimester (GW 13-25) vs third-trimester (≥GW 26) tetanus-diphtheria-acellular pertussis (Tdap) immunization...

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Maternal immunity provides protection against pertussis in newborn piglets.

Pertussis continues to be a significant cause of morbidity and mortality in infants and young children worldwide. Methods to control the disease are based on vaccination with either whole-cell or acellular vaccines or treatment with antibiotics. However, despite worldwide vaccination infants are still at the highest risk for the disease. Here we used our newly developed newborn-piglet model to ...

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Evaluation of maternal antibody levels for establishing the vaccination program against Newcastle disease in ostrich chicks

  Newcastle disease virus (NDV) is known as one of the most important endemic viral pathogen for various avian species such as ostrich, in Iran. Therefore, establishing a routine vaccination program against ND in ostrich flocks would be useful in order to reduce the danger of this infection. Newcastle disease occurs among the ostriches and leads to high rate of mortality while most of the losse...

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Maternal pertussis vaccination is associated with higher levels of pertussis

32 Maternal pertussis vaccination is associated with higher levels of pertussis 33 antibodies at birth. We assessed the persistence of pertussis antibodies until 34 primary vaccination in infants whose mothers received Tdap (tetanus, 35 diphtheria, acellular pertussis) vaccine during pregnancy. Infants were born at 36 the Hospital Clinic of Barcelona (Spain) in November 2014. Anti-PT IgG was 37...

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Protection Against Pertussis.

Though vaccines have been in use for over seventy years, we have been unable to eradicate or control pertussis. This disease is a worldwide problem, and recently has been occurring in outbreaks even in places with good immunization coverage. The debate about the use of acellular or whole cell vaccine has taken attention away from the other significant issues. The high rate of serious disease an...

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ژورنال

عنوان ژورنال: BMJ

سال: 1977

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.6088.706